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La salud de la mujer / Woman's Health

11 Diciembre 2008

Cola y osteoporosis

El consumo de bebidas tipo colas tienen efectos negativos sobre el riesgo de osteoporosis. Al parecer, estas bebidas (4 veces por semana) reducen la densidad mineral ósea (DMO) en tres puntos diferentes de la cadera aunque no en la columna vertebral.

Aging Coke BillboardEl efecto no lo producen todas las bebidas gaseosas carbonatadas, solo las que contienen ácido fosfórico como coca.cola o pepsi. Lo que es más interesante es que las mujeres objeto del estudio tenían una buena ingesta de calcio a partir de otras fuentes y los efectos se producen con tan solo 4 latas semanales de las citadas colas.


Tucker KL, Morita K, Qiao N, Hannan MT, Cupples LA, Kiel DP.

Colas, but not other carbonated beverages, are associated with low bone mineral density in older women: The Framingham Osteoporosis Study. Am J Clin Nutr 2006 Oct;84(4):936-42

Jean Mayer US Department of Agriculture Human Nutrition Research Center on Aging, Tufts University, Boston, MA 02111, USA. katherine.tucker@tufts.edu

BACKGROUND: Soft drink consumption may have adverse effects on bone mineral density (BMD), but studies have shown mixed results. In addition to displacing healthier beverages, colas contain caffeine and phosphoric acid (H3PO4), which may adversely affect bone. OBJECTIVE: We hypothesized that consumption of cola is associated with lower BMD. DESIGN: BMD was measured at the spine and 3 hip sites in 1413 women and 1125 men in the Framingham Osteoporosis Study by using dual-energy X-ray absorptiometry. Dietary intake was assessed by food-frequency questionnaire. We regressed each BMD measure on the frequency of soft drink consumption for men and women after adjustment for body mass index, height, age, energy intake, physical activity score, smoking, alcohol use, total calcium intake, total vitamin D intake, caffeine from noncola sources, season of measurement, and, for women, menopausal status and estrogen use. RESULTS: Cola intake was associated with significantly lower (P < 0.001-0.05) BMD at each hip site, but not the spine, in women but not in men. The mean BMD of those with daily cola intake was 3.7% lower at the femoral neck and 5.4% lower at Ward's area than of those who consumed <1 serving cola/mo. Similar results were seen for diet cola and, although weaker, for decaffeinated cola. No significant relations between noncola carbonated beverage consumption and BMD were observed. Total phosphorus intake was not significantly higher in daily cola consumers than in nonconsumers; however, the calcium-to-phosphorus ratios were lower. CONCLUSIONS: Intake of cola, but not of other carbonated soft drinks, is associated with low BMD in women. Additional research is needed to confirm these findings.

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